Bill Paxton
Morgan Earp

Billy Bob Thornton
Johnnt Tyler, premier croupier à l'Oriental

Billy Zane
M.Fabian

Buck Taylor
Turkey Creek Jack Johnson

Dana Delany
Josephine Marcus

Dana Wheeler-Nicholson
Mattie Blaylock Earp

Harry Carey Jr.
Freddy White, Marshall de Tombstone

Jason Priestley
Billy Breckinridge

Joanna Pacula
Kate Fisher

Jon Tenney
John Behan, Sheriff du Cochise County

Kurt Russell
Wyatt Earp

Michael Biehn
Johnny Ringo

Michael Rooker
Sherman McMasters

Pat Brady
Milt Joyce, propriétaire de l'Oriental

Peter Sherayko
Texas Jack Vermillion

Powers Boothe
Curly Bill Brocious

Sam Eliott
Virgil Earp

Stephen Lang
Ike Clanton

Thomas Haden Church
Billy Clanton

Val Kilmer
Doc Holiday