Alonzo Brown
Miller, infirmier

Brad Dourif
Billy Bibbit

Christopher Lloyd
Taber

Danny DeVito
Martini

Dean R. Brooks
Dr. John Spivey

Delos V. Smith Jr.
Scanlon

Dwight Marfield
Ellsworth, malade qui danse

Jack Nicholson
Randle Patrick McMurphy

Josip Elic
Bancini

Kay Lee
Surveillante de nuit

Louisa Moritz
Rose

Louise Fletcher
Mildred Ratched, infirmière en chef

Mel Lambert
Chef du port

Mews Small
Candy

Mimi Sarkisian
Infirmière Pilbow

Mwako Cumbuka
Warren, infirmier

Nathan George
Washington, infirmier

Peter Brocco
Colonel Matterson

Scatman Crothers
Orderly Turkle

Sydney Lassick
Charlie Cheswick

Vincent Schiavelli
Frederickson

Will Sampson
Chief Bromden

William Duell
Jim Sefelt

William Redfield
Harding